DeAndre Hopkins had 151 yards receiving, including a key reception in overtime, and Ka'imi Fairbairn's 36-yard field goal lifted the Houston Texans to a 19-16 win over the Dallas Cowboys on Sunday night.
The Cowboys got the ball first in OT but had to punt when Zach Cunningham stopped Ezekiel Elliott for no gain on third-and-1.
A 49-yard catch and run by Hopkins got the Texans in scoring range in overtime. He grabbed a short pass from Watson and twice spun away from would-be tacklers to stretch the play.
Houston was just 1 of 5 in the red zone on Sunday with Fairbairn making four field goals to help the Texans to the victory.
It is Houston's first win over the Cowboys (2-3) since the team's first game on Sept. 8, 2002, ending a three-game losing streak to Dallas. The Texans (2-3) did it in front of a franchise-record crowd of 72,008, which was peppered with plenty of Cowboys fans.
Deshaun Watson threw for 375 yards with a touchdown and an interception for the Texans , who won in overtime for the second straight week.
Dak Prescott had 208 yards passing and a touchdown but threw two interceptions for the Cowboys. Elliott, who entered the game as the NFL's leading rusher, was limited to 54 yards rushing.
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The Texans were driving late in the fourth quarter when Xavier Woods intercepted Watson, who threw under heavy pressure, with 10 seconds left and returned it 15 yards to give Dallas the ball at its 47. Kareem Jackson nearly intercepted Prescott on the next play before his Hail Mary on the last play of regulation was knocked down in the end zone by receiver DeAndre Hopkins, who came in to play defense.
A 27-yard pass interference call by Byron Jones on a ball intended for Hopkins got Houston to the 1-yard line in the third quarter. But two failed running plays followed by an incomplete pass forced another field goal which gave the Texans a 16-13 lead with about 8 1/2 minutes remaining.
The Cowboys tied it up on a 48-yard field goal with less than six minutes left. That drive was highlighted by a 44-yard pass by Prescott to Tavon Austin that he made after escaping sacks by J.J. Watt, Brandon Dunn and Zach Cunningham.
Prescott's second interception came when Johnathan Joseph broke up a pass and rookie Justin Reid caught it just before it hit the turf in the third quarter. The Texans drove to the 3-yard line on the ensuing possession before the drive stalled and Fairbairn kicked a 21-yard field goal to tie it at 13-13.
Hopkins fumbled after a catch early in the third quarter and it was recovered by Jourdan Lewis and returned to the Houston 16. The Cowboys regained the lead when Prescott found Allen Hurns in the back of the end zone on a 3-yard touchdown pass that made it 13-10.
The Texans drove to the 2-yard line later in the second but Watson's pass on third down fell incomplete and they settled for a 20-yard field goal to push the lead to 10-6.
The Texans took their first lead when rookie Keke Coutee, who made his debut last week, scored on a 1-yard run early in the second quarter. Coutee celebrated his first career touchdown with a dance called the Shiggy Challenge from a Drake song called "In My Feelings" which includes the line: "Kiki do you love me?"
Houston RB Lamar Miller, who dealt with a chest injury this week, was active but did not play. ... Texans CB Kayvon Webster left the game in the first quarter with a quadriceps injury and didn't return.
Cowboys: Host the Jacksonville Jaguars next Sunday.
Texans: Host the Buffalo Bills next Sunday.