Abrams the 7-year-old Bengal Tiger has been living at In-Sync Exotics since August 30, 2010.
JPMorgan Chase awarded more than $3 million in grants to 100 charities across the country as voted on by Facebook fans.
In-Sync's friends, families and fans helped the big cat safe haven win the grant so the group can give old, maimed, unwanted and socially unadjusted exotic cats continued care.
The grant will also help In-Sync build a new enclosure for cheetahs Sam and Kodi.
Bat World Sanctuary also finished in the Top 100 and received a $25,000 grant thanks to Facebook voting.
The group rescues thousands of bats, including those that have been orphaned, injured and confiscated from the illegal pet trade. They even give lifetime sanctuary to bats retired from zoos and research facilities.
The group not only provides rehabilitation and sanctuary but also works on the protection and conservation of wild bat colonies.
Two other Texas charities were awarded $25,000 each; Crossmen Productions, Inc. in San Antonio and Equality Texas Foundation in Austin.