Police said a sport utility vehicle rolled on Interstate 30 near East Loop 820 in Fort Worth Monday morning.
The SUV driver was heading east on I-30 when he drove off the road, struck a junction box, tipped over and rolled back onto the road under the Loop 820 overpass.
MedStar officials said they transported the driver to John Peter Smith Hospital in serious condition.
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Officials have not yet said what caused the driver to crash.