Police closed northbound I-35E at State Highway 190 in Carrollton after a fatal wreck late Sunday night.
Officers said a driver drove through the median around 8:40 p.m. The vehicle flipped over a concrete barricade and landed on the northbound I-35E between 190 and Frankford Road.
She died at the scene. Police have not released the driver's name. No other vehicles were involved.
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The on ramps from eastbound and westbound George Bush Turnpike were also closed while the investigation continued.