Cowboys linebacker DeMarcus Ware and running back Marion Barber left Thursday's game against Seattle because of injuries.
Ware had three sacks, taking over the NFL lead with 15, before he sprained his left knee late in the third quarter. Ware got hurt when his leg twisted awkwardly when he was rushing the quarterback.
After being tended to on the field by Cowboys trainers, Ware walked off under his own power. But the team said he wouldn't return.
That came just minutes after Barber had gone to the locker room because of a bruised right foot.
Barber got hurt late in the first half, and went to the locker room before halftime. He came back after the break, but ran only one more time.
After a 4-yard run midway through the third quarter, he went to the sideline and was out of the game for good.
Barber had nine carries for 32 yards, including a 2-yard touchdown in the first quarter.
Seattle's Julius Jones, playing his first game against his former team, sustained a head injury in the second quarter and didn't play until midway through the fourth.