Police closed northbound I-35E at State Highway 190 in Carrollton after a fatal wreck late Sunday night.
Officers said a driver drove through the median around 8:40 p.m. The vehicle flipped over a concrete barricade and landed on the northbound I-35E between 190 and Frankford Road.
She died at the scene. Police have not released the driver's name. No other vehicles were involved.
The on ramps from eastbound and westbound George Bush Turnpike were also closed while the investigation continued.