Garrett Gilbert ran for two touchdowns and passed for another, leading SMU to a 34-6 victory over Southern Miss on Saturday night.
Gilbert had scoring runs of 36 and 19 yards and hit Darius Johnson for a 9-yard score. He rushed for 94 yards and was 27 of 43 passing for 249 yards.
Zach Line added 92 yards rushing and a touchdown for the Mustangs (5-5, 4-2 Conference USA), who are seeking their fourth straight bowl berth.
It was the 41st career touchdown for Line, who ranks second on the school's all-time rushing list behind Eric Dickerson.
Southern Miss (0-10, 0-6) managed just 178 yards of offense. The Golden Eagles' only score came on a 15-yard TD pass from Chris Campbell to Dominique Sullivan in the second quarter. The PAT was blocked.