Cowtown event organizers expect up to 27,000 people to run in this weekend's race, an all-time record for the 35-year-old event.
The Will Rogers Memorial Center opened at 11:30 a.m. Friday so runners could pick up their bibs and get their T-shirts. Dozens of vendors were there as well to greet the runners.
There are five different road races this weekend, with distances from three miles up to more than 30.
About 2,000 more runners are participating this year compared to last year.
The race's executive director, Heidi Swartz, said that speaks to the sports growing popularity throughout the Metroplex.
"We're excited that so many people are interested in running, and running is getting more popular. We have a lot more kids this year than ever, and that's one of our goals to get more children to participate," Swartz said.
The race course wind through many of Fort Worth's most famous landmarks, including the Stockyards, Sundance Square, and TCU's campus.
Race organizers said to expect road closures and traffic delays if you'll be driving near the Will Rogers Memorial Center this weekend.
The first race is Saturday morning at 7 a.m.