Publicist Stan Rosenfield says the babies, Bob and Max, were born Saturday night in Los Angeles.
Rosenfield says Mueller Sheen is "doing great," and that the father is "ecstatic."
The twins are the first children for the couple, who married last May.
Charlie Sheen shares custody of two young daughters with ex-wife Denise Richards and also has an older daughter with a former girlfriend.
What the El!?! Editorial:
Congrats to Charlie and Brooke… interesting names.
I always like to look at the names celebrities give their kids.
Sheen's first daughter Cassandra Jade Estevez, 23, second daughter Sam J. Sheen, 5, Lola Rose Sheen, 3, and then Bob and Max.